People with high basophil levels may have an infection causing inflammation, such as tuberculosis (TB) or influenza.Ī doctor may recommend medications or rest until the infection clears, after which they will order blood tests to get more accurate results. inflammatory bowel diseases (IBD), such as Crohn’s disease or ulcerative colitis.Immune reactions or autoimmune conditions that cause chronic inflammation include: High levels of basophils may indicate chronic inflammation in the body. The medical term for this is “basophilia,” and there are several possible causes: Autoimmune inflammation What does a high white blood cell count mean?īlood tests may reveal basophil levels that are too high. The BAT is a low risk test compared with the oral food challenge test, which can potentially trigger a dangerous allergic reaction. It may also help monitor the immune system’s response to food allergens. If the person has an allergy, the basophils in their blood activate specific molecules.īAT is an accurate way to confirm food allergies. The BAT involves testing for allergies by adding potential allergens to a blood sample. This test can help doctors get a better picture of the range of basophils in the blood.ĭoctors may also order a specific test called a basophil activation test (BAT) to check for particular allergens. A basophil count that is higher or lower than usual may prompt them to order additional tests.Ī white blood cell count test may be necessary to find the absolute basophil count. This means doctors can use basophil tests to identify underlying conditions and severe allergic reactions.ĭoctors use a complete blood count to check a person’s basophil levels. Basophils have short lives, between a few hours and a few days.īasophils are reactionary, meaning their number rises or falls when they sense an invader or there is an underlying condition. The granules inside basophils contain heparin, histamine, and other molecules that play a role in inflammation. Granulocytes contain granules, which release important substances that influence the behavior of other cells and other biologic substances. Eosinophils show up as red when they come into contact with eosin, which is acidic.īasophils are types of white blood cells called granulocytes. ![]() Hematoxylin is alkaline and makes basophils appear blue under the microscope. When scientists look at white blood cells under a microscope, they often use a combination of substances for staining: hematoxylin and eosin. ![]() There are different types of white blood cells, including basophils, neutrophils, and eosinophils. The bone marrow makes white blood cells, and they help keep the body healthy by clearing out invading germs, such as bacteria, viruses, and fungi. White blood cells are vital components of the immune system. Share on Pinterest The Good Brigade/Getty Images
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